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Often if a cancer "recurs" then the same chemo used the first time is ineffective or less effective. However, other chemo drugs will often work against the recurrence.
If it comes back in a different area ... well, that depends how close the area is to the original site. If the new area is far away ... like lungs or liver are distant from the breast, then while a new chemo may be effective, it likely will not be able to "cure" the patient. If the recurrence is in the same breast, the new chemo may be able to put the recurrence into full remission. Cancer tends not to "jump" to the other breast ... though a new cancer can occur in the other breast.
I believe your wife had AC followed by Taxol. So if she were to recur, there are many other chemo drugs that they might choose to fight it a second time.
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