Can you develop a tolerance to acetaminophen?

[Brandon]

I'm wondering because after 4,000 mg it becomes toxic to the liver i've heard. But i know some people who can take 10 loratabs at a time

[Neela]

You can become tolerant to anything if you take it regularly, you can also get neuro poisoning that way. Others have a higher tolerance to different drugs, so they can take more pills with a different effect than someone who had just taken one. So it really all depends on your personal tolerance, but yes if you take it regularly.