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Taking ibuprofen for a few days during first trimester is ok, provided that you'll take the drug ONLY AS NEEDED. Also, as for any other drug to be taken during pregnancy, take the lowest dose possible. However, it's not advised for chronic pain relief, particularly in the last trimester of pregnancy, particularly after about 32 weeks. The reason for this is that as your due date nears, drugs like ibuprofen (NSAIDs) may cause premature closure of a major blood vessel near the baby's heart called the ductus arteriosus. If this happens before your baby is born (and breathing air), it will probably die.
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