reconstitution of vancomycin powder?

[ski fan]

How would 500mg of vancomycin powder be reconstituted to form 10mg vancomycin in 4ml water for an intrathecal injection?

[Robert D]

Dissolve the 500 mg into 200 cc of water.

Each cc will contain 2.5 mg of vancomycin.

Thus 4 cc will contain 10 mg.

Not sure I'd inject that into anything. Surely you would use an isotonic solution? But hey, I'm a scientist, not a pharmacist.