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Old 03-08-2009
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Can an epileptic such as Lamictal prevent seizures that can happen from mixing Tramadol and Ziprasidone
*antiepileptic
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Old 03-09-2009
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Maybe so, but it would make sense to drop the Tramadol.

Each drug lowers the seizure threshold (the amount of stimulus needed to provoke a seizure), and if your prone to seizures then than can be a problem.

Lamictal is not a broad acting acting antiseizure drug as dilantin, nor has it been used as long to establish drug interactions.

What I really do not like about Lamictal is the Stevens Johnson allergy and the anti-folate activity. It looks like to me is that it is a drug put on the market to make money not some breakthrough improvement in choices for the physician.

Those atypical antipsycotics like Ziprasidone promote weight gain and diabetes, I would minimize this therapy to the very , very , least.
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Old 03-09-2009
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First, it is not advisable to mix tramadol & ziprasidone since doing so would increase the risk of seizures associated with tramadol. It would not be wise to continue to take both knowing the above effect then taking an anti-epileptic drug to counter it.

Lamictal is not advisable to be given in patients taking ziprasidone since it can cause excessive or prolonged CNS and respiratory depression. Both drugs has central nervous system- and/or respiratory-depressant effects.
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