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That symptom is also known as chemo-induced peripheral neuropathy (the numbness, occasionally with tingling sensation) since some chemo drugs cause damage to the peripheral nerves.
Other symptoms of peripheral neuropathy:
Numbness, tingling (feeling of pins and needles) of hands and/or feet
Burning of hands and/or feet
Numbness around mouth
Constipation
Loss of sensation to touch
Loss of positional sense (knowing where a body part is without looking).
Weakness and leg cramping or any pain in hands and/or feet
Difficulty picking things up or buttoning clothes
Although some of the signs of neuropathy may appear suddenly, this change in sensation usually builds gradually and can worsen with each additional dose of chemotherapy. It is usually strongest right after a chemo treatment, but tends to lessen just before the next treatment. The symptoms usually peak about 3-5 months after the last dose of treatment is taken. The abnormal sensations may disappear completely, or lessen only partially; they may also involve less of the body. If neuropathy diminishes, it is a gradual process usually requiring several months. However, in some cases it may be irreversible and never diminish in intensity or the area of the body affected.
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