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As previously stated, this is the old system of weighing. Also, as you have already stated, the XX is the roman numeral for 20, as each X is equal to 10 units.
The gr. unit stands for grains. 1 grain is equivalent to 64.8 mg, so the 20 grains (XX gr.) of Nembutal is equal to 1296 mg.
This is found by using dimensional analysis to convert the units, which i'm sure you know how to do.
20 grains * 64.8 mg/grains = 1296 mg.
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