Would piracetam really be safe and decent to take with pharm anti epileptic drugs? I'm curious to know if anyone has taken this with any of their meds. Thanks.
Piracetam improves most aspects of mental function in Epilepsy patients without interfering with anti-epileptic pharmaceutical drugs: Chaudhry, H. R., et al. Clinical use of piracetam in epileptic patients. Curr Ther Res Clin Exp. 52(3):355-360, 1992.
Sources of info: smartdrugsforthought.com/piracetam-research they also have a downlaodable PDF that mentions testing with patients that have epilepsy.
Ritalin is lower intensity and shorter acting than adderall. Used in conjunction with adderall it is highy effective however.
Just wanted to drop my .2 cents.
Ritalin and Adderall differ in more than just their release profiles.
Ritalin is methylphenidate, and Concerta is simply a time-release version of methyl phenidate.
Adderall on the other hand, is a combination of dexamphetamine salts.
Methylphenidate acts only on DA receptors, with dexamphetamine salts act on both DA receptors, and Norepinephrine (also known as Noradrenaline) receptors.
Generally speaking, Adderall is more powerful of the 2, and is more addictive, due to the one-two combo of both of those very powerful neurotransmitters.
Release profiles have more to do with how the drug is constructed, than what the drug actually does.
Just my thoughts, didn't want to step on anybody's toes, but it is worth noting that these are not the same chemical compound, and as a result, should not be treated as such.
I noticed my body different on Adderall and Ritalin. When taking Adderall I feel way more energetic then Ritalin but once Adderall wears off I have to sleep atleast 10+ hours to get back what i loss. Now when im on Ritalin i don't have this energetic effect but I do have way more focus then adderall but after awhile my body gets to twitch?
These are my personal experiences with them but if you wanted to know information chemically then @Palchod post explains alot of that. If you didn't see his post for some reason imma quote it.
Your different response totally make sense. The norepinephrine has a much stronger "energy" effect. Norepinephrine is also known as Noradrenaline. So it is reasonable to assume that your body is responding to the elevated NE. When you come off, there is a harder crash, because those NE neurotransmitters have been used up, and your body wants to sleep in order to recover.
Some people do find that the "psychologica crash" off of Ritalin is harder, as they find themselves depleted of Dopamine, but still somewhat energetic, albeit "depressed."
Others find the crash off or Aderral worse. A lot with come down to the variable biochemistry between different people.
The twitching is a normal response to elevated levels of DA. Though it is somewhat disconcerting at first.
Some people find Aderall to be less of a focusing agent than Ritalin, which may seem strange, but the elevated levels of NE (think "energy"/"strong stimulant") lead to a distraction for some people.
Again, this is a lot of anecdotal evidence mixed in with some basic-level biochemistry.
I'm always open to hearing other things and getting other opinions.
I would say that adderal is better for studying/concentration, though the comedown for me is much worse on it, if you can get just Dextroamphetamine that is the best. It seems to feel the cleanest. That being said, Ritalin will most defiantly work as a study aid if nothing else is around.
That is interesting. Dextroamphetamine (Dexedrine, otherwise known as "Dex" I am going to assume) is just the d-isomer of dexamphetamine. Adderall consists of both the l and the d isomer of dexamphetamine. That is really the only difference (let's ignore the fact that Adderall has a variety of salts that release in a different pattern).
That means that you are responding better to the d-isomer.
This makes sense as a lot of anecdotal evidence suggests that the l-isomer is what causes anxiety, apprehension, etc when taking Adderall, aka, "those shitty last couple of hours and come down."
Anyway, just my two cents. Thanks for your feedback man.
"A person who has never made a mistake, has never tried anything new."
I think you're confused about what a 'nootropic' is...benzo's and piperidine cocaine analogues have serious side-effect profiles and a very narrow therapeutic window. Which is the exact opposite of Dr. Corneliu E. Giurgea's definition. (He coined the term, so I'll trust him)
Just don't like terms getting misused. You may know what you meant, but obviously other people don't pay attention when they're on the internet, assuming things as fact, and then wind up posting which psychostimulant is better in the epilepsy subforum!
Nothing helps people stop convulsing like speed...
For a thread about anti-seizure medication - below find a list of medications that are currently approved and marketed for certain kinds of epilepsy. Not sure that ritalin and adderall made the list.
Ive tried Vyvanse, Adderall XR, Adderall IR, Concerta, and methylphenidate. I found Concerta to have the smoothest onset and less peaks/valleys during the day. But I found when Concerta crashes, it really crashes. I'm fairly happy with Addrerall XR at the moment. Both are fairly comparable (if you get the dose right) but amphetamines are generally stronger than MPH. Best way to view this is a bathtub with the drain removed (the water is dopamine and norepinepherine). MPH just plugs the drain allowing the dopamine and norepinepherine levels to increase. Amphetamines plug the drain and open the tap increase the levels of dopamine and NE.