I wouldn't suggest taking 2 at once because it will upset your stomache. My doctor had me on 1 a day for a week so my body could get used to it. I will say the first week I started taking 2 a day I had the worst burning diarrhea and stomach pain omg. Luckily it went away and I was able to take them with no discomfort. It was all worth it in the end because I got pregnant 3 weeks after I started Metformin. Now I have a 1 year old girl who is everything I ever wished for. Dreams do come true and Metformin can help you get there. Good luck!