Aurochem Tadalafil problem

[Zanbato]

When I dose on Aurochem tadalafil (the little yellow oblong tabs with e-20 engraved on one side) I tend to get a pretty satisfactory and controllable response. The stuff is excellent. (Props, Generic4all.)

However, there are some uglier side effects I feel the need to discuss. The other day I accidentally took a second full-dose a little too early. (The effects of tadalafil, on me at least, from Aurochem usually last somewhere in the ballpark of 3 days, with a gradual tapering off occurring usually at some point during the third day.)

When I accidentally took a second dose too soon, I was beset within a couple of hours with an extremely painful headache. I genuinely don't think I had a worse headache in my life, even hungover. I needed a huge dose of ibuprofen to (only partially) allay the giant headache. Consider this post a warning: Don't overdose on Aurochem's tadalafil: it hurts!

Another problem I've encountered is that I think the tadalafil I ordered from Generic4all (Aurochem) is making me sick. Every couple of doses I take, I start to get a really dry cough, "frog" in my throat, and extremely runny nose. These effects last well outside the half-life of the drug in my system and I think are a little more serious than the usual "stuffy nose", etc, etc side effects associated with the drug. For the last couple of months, I've been dealing with an on-again-off-again cold. I know the cause of this cold couldn't be extraneous to the drugs I'm taking. Otherwise, I'm a healthy guy and don't get sick any more often than the average person.

I'm not sure there's a correllation but I seem to be getting sick and awful lot...and that coincides directly with the frequency of my dosing on tadalafil manufactured by Aurochem AND the "generic vardenafil" that comes in the "ED Trial Pack" offered by Generic4all.

Has anyone else had experiences like this?

[pillman]

@Zanbato, do the blister packs for your pills have "Code No: MH/DRUGS/KD-19" printed on them?

[Leeroy909]

I got the same thing a couple of time after taking "Megalis" Tadalafil. I will report back if it happens again, you should do the same.

[juniperpansy]

However, there are some uglier side effects I feel the need to discuss.

Zanbato please email generic4all and let them know about this. It is possibly a bad batch. If people let them know there is a good chance they will look into it and possibly fix it.

OTOH if eveyone just assumes 'indian generics are crap' and nobody bothers to write them then obviously the problem is less likely to get sorted

[Zanbato]

@Zanbato, do the blister packs for your pills have "Code No: MH/DRUGS/KD-19" printed on them?

They don't, but a couple of them have MRP in blank ink printed on them with a string of letters and numbers after it that I can't read because it's been crossed out with what looks like a black marker. What's up with that?

Zanbato please email generic4all and let them know about this. It is possibly a bad batch. If people let them know there is a good chance they will look into it and possibly fix it.

I emailed them Thursday about the problems and have yet to hear back from them.

I should probably add that I've tried to e-mail them before about this, only to be ignored.

OTOH if eveyone just assumes 'indian generics are crap' and nobody bothers to write them then obviously the problem is less likely to get sorted

It only happens sometimes, so I hesitate to say anything categorical about Indian generics as a whole. Perhpas it was a bad batch. What troubles me is that customer service seems content to let me fall through the cracks when it comes to this problem, as I've gotten no correspondence from them yet, this being my second attempt.

[Zanbato]

Turns out they don't deal with problems with their meds more than 3 months after meds are purchased. What horse shit.

[McLuvin]

Interesting post.
I will add that of the 3 ED meds, Tadalafil gives me the worse side effects. I have never taken any version beside the Cipla one. It does do it's job, no doubt. However, I too would get flushing, slight headaches, weird pains, gastric upset, etc. I don't think it was a bad batch, I think it's just Tadalafil. I no longer take it, it's just sitting in my cabinet. V works better w/ less sides (for me anyway). L last longer (again, imho..) however, I was getting mild headaches from that after a while also.

I think Tadalafil's half life is like 17-18 hours, stays in your system for much longer tho. Because of the long HL, it's levels are cumulative. As long as there is 'some' floating around in your system, taking another dose will just be boost that level. I could see how someone taking a full dose 2 days in a row, would have a level that was over the top. Sides would be quite severe.

I was looking at this chart this morning. If someone took 20mg dose, 24 hours later, they'd still have about 150 micrograms floating around. If they took another does on top of that, the peak would be something like (340-350 + 150 =) 500 micrograms per L. Yowza.

[Magician]

I think it's just Tadalafil. I no longer take it, it's just sitting in my cabinet. V works better w/ less sides (for me anyway). L last longer (again, imho..) however, I was getting mild headaches from that after a while also.

Since you sait tadalafil (not Cialis) does that mean "V" is vardenafil? Or is "v" for viagra/sildenafil, since later you said "L" which I guess is for levitra? Or is "L" for Lodenafil (the new Brazilian boner pill, branded "Helleva")? If you really got ahold of some Lodenafil carbonate, I would really like to hear some comparative observations from you! And where did you get it?

I was looking at this chart this morning....

Very nice chart, can I ask the source? I'm not doubting it, I just like to know where to look for useful info like that! I noticed two more points from that chart, firstly that the blood level after an hour is at about 130 ug/L, and that's where we begin to see the positive effects, although peak levels of 350 ug/L don't occur until several hours after dosing--which is probably when those nasty side-effects kick in. Secondly, blood levels with 5mg daily dosing, at day 5-6, keeps the concentration around 100-175 ug/L, so the 5mg regimen seems like it would be useful for keeping the drug at a useful level, without the spikes that could aggravate side effects. So the 5mg regimen looks like a great idea, albeit an expensive one. But useful for a person who's sexually active on a regular/frequent basis.

[insureu]

@Zanbato, do the blister packs for your pills have "Code No: MH/DRUGS/KD-19" printed on them?

I received my newest order today. It has D2019M4/12E3/15 on each of the blister packs. I always get a slight tense neck and a flushing around my face for a few minutes about 30 minutes after I take it. These side effects go away. I have such horrible sinus problems that I can't attribute anything to aggravating my sinuses.

Not meaning any disrespect but you did take two of the pills which I am quite certain would give me a neck/headache. I've used their products for a year or so with no difference between these and domestic brand name other than the huge $ difference.

[McLuvin]

Magician,
Sorry, I have my own shorthand, making my post unclear. V=Viagra, L=Levitra. Sorry if that confused anyone.

That pic is hotlinked (sorry if that's now allowed?), it's addy is http://dailymed.nlm.nih.gov/dailymed...pi-f001-v2.jpg. You can right click it and view it's location. It's pointing to the Nat'l Library of Medicine site. It was embedded in an article comparing blood levels when taking the typical Cialis dosing method vs the smaller Daily version.


Cheers!

Since you sait tadalafil (not Cialis) does that mean "V" is vardenafil? Or is "v" for viagra/sildenafil, since later you said "L" which I guess is for levitra? Or is "L" for Lodenafil (the new Brazilian boner pill, branded "Helleva")? If you really got ahold of some Lodenafil carbonate, I would really like to hear some comparative observations from you! And where did you get it?


Very nice chart, can I ask the source? I'm not doubting it, I just like to know where to look for useful info like that! I noticed two more points from that chart, firstly that the blood level after an hour is at about 130 ug/L, and that's where we begin to see the positive effects, although peak levels of 350 ug/L don't occur until several hours after dosing--which is probably when those nasty side-effects kick in. Secondly, blood levels with 5mg daily dosing, at day 5-6, keeps the concentration around 100-175 ug/L, so the 5mg regimen seems like it would be useful for keeping the drug at a useful level, without the spikes that could aggravate side effects. So the 5mg regimen looks like a great idea, albeit an expensive one. But useful for a person who's sexually active on a regular/frequent basis.

[deven59]

I had ordered the same thing from A2ZePharma and this worked for me but the thing is my physician advised me the dosage. I think you should consult about your dosage and also check the blister to see if its expired.

[Zanbato]

Not meaning any disrespect but you did take two of the pills which I am quite certain would give me a neck/headache. I've used their products for a year or so with no difference between these and domestic brand name other than the huge $ difference.

Yeah, that explained my headache away pretty well. That was a mistake made in the heat of the moment. (Thought I'd need the extra "boost" for a lady I was going to be with that night, underestimating how long the other dose would stay in my system.)

That, however, doesn't explain the frog-in-the-throat-symptoms. They last for a while after I dose. Sometimes even more than a few days.

Even more startlingly, I ordered a fresh batch of different pills. For the last few weeks I've been trying "Zhewitrasoft": basically "Vardenafil softtabs." It would seem that every time I take one of those, I can almost expect painful lower abdominal cramping and weird mucousy stool.

I'm not instantly assuming that the "zhewitrasoft" is causing it, but there does seem to be a pattern emerging here...

[BEXTOR]

I don't think your simptoms are caused by a bad patch of tadalafil. I think you can blame on Tadalafil itself. My advise is that you should try other dosage. Try to have only 10mg each time. I found out that it's the perfect dosage for me and most of the people. Taking any more may only increase the side effects, and don't make you feel much more of the intended perform. You can try this and explain us if this improved your experience.

[asco]

Well, I had Megalis twice, 20mg and half a pill, 10mg. At the first try I had a flu like symptoms and an awful back pain. This lasted for 4 days!!
The second time, 10mg, same side affects but only for two days.
I had the desired effect but could not move, walk...

I have La pela on hand but I guess I won't be using it as it's also Tadlafil.