The reason i joined this forum is because I am/was looking for an antidepressant/anxiolytic called Stablon (tianeptine).
I have been using fluoxetine and escitalopram under my dr's supervision without much success. All these meds did is kill my libido and made mee feel like an idiot. My doctor wants to put me on a TCA now (anafrinil) but i decided i first want to try Stablon because i've seen good reviews about it and the way its promoted to work makes sense to me. And I hate the fact that TCA's have strong anticholinergic Side effects, allthough i don't know in what degree they will affect me.
It's an SSRE (Selective serotonin reuptake enhancer) so the opposite of an ssri. Users report a non-sedative anxiolytic and antidepressant effect without the nasty side effects SSRIs are known for (like feeling numb and sexual side effects). Allthough the exact mechanism of action is unknown, it is demonstrated that stablon increases neurogenisis in certain areas of the brain (especially the hippocampus) and thereby restoring damage that is caused by an excess of stress hormones. Just like ssri's do in a lesser degree (and with alot more side effects).
This theory sounds a lot more plausible to me then the serotonin deficiency theory that has been spreaded by pharma companies since the launch of prozac.
Also enhancing the serotonin reuptake is believed to increase dopamine levels in some parts of the brain, which could also be a partial explaination of tianeptine's antidepressant, but not its anxiolytic, effect. Because of this increase of dopamine, tianeptine also seems to be moderately effective (allthough not as much as stimulants) in treating ad(h)d. This is another reason why i have the feeling this drug might be suitable for me. I have ADD and SSRI's make it alot worse (probably because the excess serotonin decreases dopamine activity).
Anyway i would like to hear from people who have used this medication, if there are any on this forum. More info on tianeptine can be found at tianeptine.com