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Thread: What is an abnormal liver function result and could it be a side effect of morphine

  1. #1
    Neil S is offline Junior Member
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    Feb 2008
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    Default What is an abnormal liver function result and could it be a side effect of morphine

    My husband has been on morphine capsules for over 2 years for pain caused by Ankylosing Spondylitis. Doctors have said pain management is the best we can hope for. But now his liver function tests have come back at 83? Apparently 40 is normal and his is 83. I don't know what this means. We have an emergency appointment with GP tomorrow but does anyone know what this means? They asked him if he drinks alcohol (he doesn't) which led me to think it must be bad.
    He's on morphine, tramadol, celebrex, gabapentin al heavy duty painkillers - could they be damaging his liver? I'm so worried but feel like I can't ask the doctor a million questions with my husband present because I don't want him to know I'm so worried. He can't work and doesn't get any benefits because I work full-time. He's been refused for Disability so he worries about the future a lot and gets depressed a lot. If anyone has any medical knowledge / general advice I'd be very grateful.

    Ps. My husband is only 35 years old and we live in the UK

  2. #2
    Someones' Mom is offline Junior Member
    Join Date
    Dec 2008
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    You have some wonderful questions. And you may have to tell your husband to be prepared, because you are going to address your questions with his doc. And if he has a problem with that, he can sit in the car.

    You have every right in the world to know what is going on with your mate. Anyone would be worried since your husband has a condition that carries with it very few options for treatment. You wrote this:" I'm so worried but feel like I can't ask the doctor a million questions with my husband present because I don't want him to know I'm so worried."

    I am sure you have your reasons for not wanting your husband to know that you are worried......I personally would be worried, as it seems a normal reaction toward someone you love. And maybe if he had a little idea as to how you are trying to educate yourself about his condition, he may just feel a little better.......

    The liver is a filter and carries with it over 400 functions. EVERYTHING we injest goes through the liver. He is taking a lot of medications. His function shows working overtime.....can ask the doc how to get those values down.

    Any medication we take can wreak havoc on our livers. The morphine, made from poppys, may be having less effect than the gabapentin (anti seizure used for neuropathy and pain, mood), Celebrex (antiinflammatory) tramadol (non narcotic pain for mild to moderate relief). If your husband is feeling some depression, I would expect him to be on an antidepressant as well. (It could be that the liver is being affected by the AS as well).

    I believe you have every right to be worried, and a wonderfully supportive wife......if your husband doesn't know this, he should!!

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