Tramadol and Hydrocodine

[mthomas46]

Tramadol doesn't hold a candle to opiate pain killers, but it is slightly more effective than ibuprofen or acetominiphen. You can become addicted to it, and you can develop a tolerance to it, so although it doesn't work as well as an opiate, it comes with all the unwanted baggage. Some people say withdrawal from tramadol is worse than opiates.

[zackery]

I found the reactions to Tramadol were so bad that I told my doctor, I don't want them.

I could not sleep, I was dizzy. But a friend of mine took them, and they worked great. Bottom line, it was the first drug I took that gave me such a bad reaction that I never wanted to take them again. Sleeping to me is number one. Without sleep, you are pretty much worthless during the day.

But if they work for you, that is great. No withdrawal when you run out. No issues, and much easier to get. If they work for you, that is really good news.

We all are different and how we react to certain drugs. I hope they don't start saying they are in the same category as hydos -- or something stronger, that would be a mistake. What are we supposed to take nothing when we have pain issues. Nuts.

[Perromaldido]

Just beacause it keeps major opiates wd at bay it should be spoken high of. I wish I had it back in the '80s. And yes, definitely affects different people in different ways. For me it's just okay though my intake in higher than thr maximum daily one suggested

Perromaldido

[emerald]

Tramadol apparently is very easy to get addicted to and people say the withdrawals are hell.

I believe hydrocodone treats pain more immediately than Tramadol, but Tramadol is effective if you have it in your system more long-term. But again, I hear people warn about awful withdrawals.

Tramadol can make you drowsy or dizzy, too, which hydrocodone doesn't always do.

[GoingBananas]

I have tried Tramadol from my latest pain Dr. and many of the above statements were what he told me. it does act on several of the chemicals anti-depressants act on in addition to being changed into a form of drug by the liver that acts as opioid on the brain. (Albeit a weak one) My experience was that I could definitely feel it when i took I took it but that was always a good thing because I felt the side effects, ( That out of it, drunk-like feeling, I do not like) more than I felt any sense of pain relief with it.

That being said I have talked to many chronic pain patients that really like tramadol and it does seem like it works really well in some case. Somone brought this up and I think there is some truth to it even in my case, I wonder how much more effective it would "seem" to be if it were scheduled and hard to obtain? The placebo in effect at all times!

[TenaciousE]

Tramadol eradicated my migraines and neck pain. But did nothing for my post surgical ankle pain.

In exchange I experienced nausea, blurred vision, constipation, difficulty urinating, cognitive impairment, forgot fullness, loss of libido and a blunted personality.

When I decided to WD from Tramadol I experienced:

Runny Nose
Intense Stomach Pain
Panic Attacks
Severe Anxiety
Severe Depression
Restless Leg Syndrome
Chills interspersed with Soaking Sweat
Muscle Aches
Brutal heachache
Insommnia

I couldn't get out of bed for four days.

So you might want to reconsider signing up for Tramadol.

[pokee123]

I have experience with tramadol. It does work very well and I find the effects very similar to hydrocodone. My doctor was very willing to prescribe it because as he said "it is non narcotic and non addicting"..well guess what?? addicting yes..I needed more after time to control pain and most definatly I went through withdrawals when I had none. And it wasn't pleasant. Sleepy , yet couldn't sleep, moody and the ole shakey legs at night..Horrible...so what's our choice when we live with pain? the pain or the chase??? tramadol works..hope my shared experience helps

[crwhitlock]

Tramadol is not an opiate, hydrocodone or vicodin is.. For someone without an opiate tolerance tramadol will give a sense of well being, I don't know if I would call it euphoria. It's a solid pain reliever but defintaley not on the same level as vicodin. I think the best way to describe it would be like motrin on steroids.

[alumni]

For what it's worth, the medical definition of an "opiate" can often be somewhat confusing.
An opiate is made from a naturally occurring product in the opium plant. Morphine, heroin and codeine are opiates and members of the opioid family of medications.
Hydrocodone, oxycodone, methadone, fentanyl, etc. are either semi-synthetic or fully synthetic compounds also classified as opioids. So Vicodin, in medical terms, is not an opiate.
Tramadol is often described as a synthetic analgesic with agonistic effects on certain opioid receptors. Thus for all intents and purposes, it acts like an opioid along with inhibiting norepinephrine reuptake in specific synapses.

[audacity]

@alumni If heroin is an opiate, then hydrocodone and oxycodone have to be included as opiates. All three are semi-synthetic (heroin from natural morphine, hydrocodone and oxycodone from natural thebaine).

[LSUCAJUNTIGER]

Arizona is going to vote Tramadol up to a scheduled drug,(I just read tonight) as I think Kentucky already did.

Those that like it should stock up. Never tried it.

Hope your state keeps allowing it for those that count on it. ~

Oklahoma already did. They did the same to Soma a couple of years ago.

I am finding it harder to find usa pharms to order from. they are telling me they can't ship to my state.

About 3 month ago Friendly did send me 180. I used my cc. I don't know if they are still shipping to my state as I have not done business with them after I found cc charges on my account that could not be accounted for after using them.

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I did order some 200mg. Tramadol from pharmamazing. It is one of the airmail sites from India.

I just break them in half. They have specials all the time. you just have to look. or you can sign up to their newsletters.

[alumni]

@alumni If heroin is an opiate, then hydrocodone and oxycodone have to be included as opiates. All three are semi-synthetic (heroin from natural morphine, hydrocodone and oxycodone from natural thebaine).

Nope. A standard 5 panel drug tox screen tests for opiate metabolites.
Hydrocodone and oxycodone will not show positive for opiates.
Heroin and morphine will. That's why most pain management practices use UA's with more than 5 panels.
As I said, the pharmacology can be confusing.

[audacity]

@alumni Heroin, morphine, codeine have a double bond where oxycodone, hydrocodone have a single bond. The single bond is enough to throw off the assay so that a separate one is needed. It doesn't mean it's not an opiate. Clonazepam often doesn't show up in benzodiazepine screens. Is it not a benzodiazepine?

What does this have to do with pharmacology? That's not the difference.

[alumni]

Well, let's try again.
Pharmacology, since you asked, is the study of drug actions including the source of drugs, their individual nature and their definitions.
Opiate has become an evolved definition in the study of drug composition and their source.
If you research this information about opiates, you will find that they are now usually defined as being derived from naturally occurring opium poppies.
You are correct that semi-synthetic painkillers like hydrocodone are derived from thebaine also but in most medical terminology today these medications are not generally described as opiates.
This is evident in the use of tox screens where substances like codeine, heroin and morphine are identified via their metabolites as opiates as opposed to the semi and fully synthetic drugs like hydrocodone. As you say, these can only be identified by specific assays.
Overall, it's simply a shorthand use of the difference and the terms are very often interchanged outside of medical jargon.

[audacity]

@alumni Oh ok. If it can be detected with an opiate assay, it's an opiate, if it has similar pharmacodynamics to opiates but cannot be detected with an opiate assay, it is an opioid. Thanks for giving me the medical definition!

[lizzy53]

Does any one know of a US based pharmacy that takes Mastercard

[Lynx4]

Does any one know of a US based pharmacy that takes Mastercard

[Perromaldido]

Well, pharmacocynetic cab be quite confusing....I don't know if O-dysmethyltramadol
shows up on a five panel test. I wanted to share what once on chemist told me, and it went like this - You can always say if a substance is an opiate/oids becuase in the molecule diagram you can recognise the 'rule of morphine. He added - it's quite well hidden in the tramadol structure but it's there. I am no chemist but this guy knows his work, so I tend to trust him. OTOH info on the net are controversial to say the least

Perromaldido

[etinin]

I think I'm one of those CYP2D6 super-metabolizers.
Codeine and tramadol work so well for me that I've never been tempted at all to take stronger opiates. Even 120mg of Codeine or 50mg of Tramadol put me very close to opium dream land and give me an enormous sense of well being.

SWIM's GF on the other hand, had a very tragic experience some other day, and SWIM gave her some tramadol to make her feel a little better. It had no effect at all. It really depends on your liver enzymes.

[Meow]

So... quick question about tram

does it give you like, instant wd? after a week? a month? or does it take months and months? or very high doses to cause wd?