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Thread: Tolerance

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    Default Tolerance

    How long would you say it takes for the body to get over its tolerance to any type of drug? I have been taking Soma now for years. I was getting US made Watson brand and it was good stuff, then my state banned Soma and i have been going the IOP route. The India stuff never seemed as strong as the U.S. Watson brand, i just figured it wasnt as potent as the U.S. made Soma. Recently i was able to sneak in a U.S. Watson brand order from a U.S. pharmacy and now they dont seem to have the same effect as years prior. I think the years of taking the drug has built up a tolerance and the effects arent what they used to be.

    Wondering how long i would have to "go sober" before the Soma works the way it used to. We talking weeks...months... a year of going without? Kinda frustrating, 90 pills used to last almost a month and now i blow through them in about 10 days. I realize that everyones body is different, but just wondering what others have experienced.
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    From my experience you never get the same feeling back as when you first started taking any medication. All that happens when you stop taking a drug it Med and then go back to it your tolerance will be back to where you left off in a matter if days and then tolerance will go even higher. Believe me I know, why do you think addicts are always talking about chasing their first "high" just my opinion but if soma not working for you anymore why nit just stop taking it as opposed to stopping for awhile and going back just to get a better feeling from it. You will never get that same feeling back like when you first started.

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    Nine soma a day sounds like an awful lot, you don't want to stop breathing or something. Milli.d you I'm not trying to preach and um certainly not judging you, just saying be careful. Sounds like your tolerance is too high and you will never get back that feeling you want from soma.
    Last edited by Coheed; 11-10-2011 at 03:14 PM.
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    for me personally I would say at least a year,but what is scary is that your tolerance returns quickly- i had a period of abstinence Little over a month and it took 8 days to be back at my original dose,time and lots of it resets tolerance,I get the feeling that even after a long period it would still return quickly for me-(opiates) I'm not sure about soma as I personally have little experience and muscle relaxers
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    I meant mind you I'm not preaching were dam phone keyboard

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    Quote Originally Posted by Coheed View Post
    From my experience you never get the same feeling back as when you first started taking any medication. All that happens when you stop taking a drug it Med and then go back to it your tolerance will be back to where you left off in a matter if days and then tolerance will go even higher. Believe me I know, why do you think addicts are always talking about chasing their first "high" just my opinion but if soma not working for you anymore why nit just stop taking it as opposed to stopping for awhile and going back just to get a better feeling from it. You will never get that same feeling back like when you first started.

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    Nine soma a day sounds like an awful lot, you don't want to stop breathing or something. Milli.d you I'm not trying to preach and um certainly not judging you, just saying be careful. Sounds like your tolerance is too high and you will never get back that feeling you want from soma.
    Well here's the confusion/frustration.... I have legit need for Soma, my back is jacked up. The normal dose worked fine and provided a short little buzz which was fun. Then the buzz disappeared but the relief was still there. Now it seems to take alot to even get to the relief stage. I am more interested in the relief than the buzz. I've had to up the dose to get relief. The "9" a day is due to the effects only lasting a few hours then taking another dose. Prescribed it was one tab four times daily. Now its like three tabs three times a day.

    If the 9 tabs arent providing relief or buzz then i cant see how 9 tabs would stop my breathing. Its like it isnt effecting me at all. Same with xanax. I am prescribed xanax and it has taken the same route where i now dont get relief from a normal dose. I DONT want to keep increasing the dose to get relief, but it seems like thats whats happening. It does still work but in increasing amounts. Kinda wondering if the Soma and Xanax have created a cross tolerance, they work with the same receptors/enzymes.

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    The concept of reducing tolerance by a period of discontinuation is almost always a flawed one when involving a psychotropic drug like Soma.
    Especially when the level of daily dosage is as high as nine tablets. That is potentially a problematic level of consumption.
    I don't believe you will be successful in lowering your tolerance like you are hoping for.
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    Even your daily dose is not providing you with relief or a buzz doesn't mean your nit having cns depression, but I am in no way an expert on the subject m just trying to help and saying be careful.
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    Quote Originally Posted by alumni View Post
    The concept of reducing tolerance by a period of discontinuation is almost always a flawed one when involving a psychotropic drug like Soma.
    Especially when the level of daily dosage is as high as nine tablets. That is potentially a problematic level of consumption.
    I don't believe you will be successful in lowering your tolerance like you are hoping for.
    Oh its becoming problamatic..... financially Not really, but i guess this is the problem with meds. Everyone takes them intially for a specific condition. Then over time the condition will still exist but the relief decreases. The condition isnt going away so its one of two choices: Live with the pain or continue to increase dose to provide relief.

    I wake up in morning and can barely sit up out of bed: Dose 1. After a hard days work and an hour drive home can barely get out of car: Dose 2. Later in evening dose 2 wears off and its time for bed: Dose 3. This is a pattern i dont see changing anytime soon. Sucks. Soma is meant for short term use, its now been about 5 years taking it. Soma works great... when it works. My dad has a neck problem and goes about every 4 months for some kind of injection.... cortisone i think. Thinking maybe that would be a better route then the increasing amount of Soma, but i'm not a doctor.

    I think about the CNS depression but i would tend to beleive that if it started becoming a problem it would be something i would feel first. Cant imagine taking increasing doses and not getting any effect or feeling then all of the sudden....BOOM... not breathing.
    Last edited by Biggin2; 11-10-2011 at 04:21 PM.
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    Quote Originally Posted by Biggin2 View Post
    Cant imagine taking increasing doses and not getting any effect or feeling then all of the sudden....BOOM... not breathing.
    Unfortunately,that's pretty much how a depressed breathing overdose usually happens.
    BOOM.
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    With my soma experiences, it took 6 months before my experiences on small amounts were similar to when I first started. But like others have said, your back to full strength in very short order, like ~10 days.

    And its next ever like the first time :/
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    Let me begin this post by stating that I currently use Soma and this is neither an "anti, or pro Soma" post.

    @Biggin2

    Soma is a chemical chameleon, one that morphs in the human body. Soma is literally two drugs in one. The first, carisoprodol (its generic name), is a muscle relaxant -- or at least, it starts out that way. Then, as it breaks down in the body, it morphs into a different drug altogether: meprobamate (Been around since the 50's)

    Meprobamate is known to produce both physical and psychological dependence. Tolerance occurs, requiring higher doses to achieve the desired effects and avoid the withdrawal syndrome. The withdrawals usually consists of anxiety, tremors, insomnia, and occasionally seizures and hallucinations.

    There is an online research article about a surveyed 20 substance abusers who had used prescription carisoprodol for 3 months or longer. Thirteen of the subjects admitted using carisoprodol in some manner other than that prescribed by their physician and 3 admitted using carisoprodol to modify the effect of another drug. The subjects have admitted using carisoprodol to augment the effect of ethanol or alprazolam and to “take the edge off the jittery feeling” from cocaine use.

    I wouldn't worry to awful much about the mentioned dosage as I recently read an article stating that A 19-year-old female survived
    the ingestion of 14.7 grams of carisoprodol/Soma. 1000mg = 1g

    With that being said, I would certainly plan on tapering if you decide to quit as you will certainly face withdrawls with a "cold turkey approach". Having ingested the quantity you are currently taking for a prolonged period of time & suddenly stopping will sting bad... But it very well maybe necessary for you to taper, quit for a period and begin again if needed to eliminate having to consume so many mg's! As far as how long to wait until tolerance has reached a certain level and blah blah blah; that is so person/individual specific I will not even address it in this post. Note that the standard dosage for adults is 250 mg to 350 mg three times daily and at bed-time. Soma will definitely build tolerance and dependence with long term use !!!

    Found this @ Carisoprodol Effects

    Dependence and Withdrawal: Development of abuse and moderate physical and psychological dependence can occur with chronic use of both carisoprodol and meprobamate. Abrupt discontinuation of long-term use can be followed by mild withdrawal symptoms such as anxiety, abdominal cramps, insomnia, headache, nausea, vomiting, ataxia, tremor, muscle twitching, confusion, and occasionally chills, convulsions and hallucinations. Onset of withdrawal from meprobamate occurs within 12-48 hours following cessation of use, and can last a further 12-48 hours. Carisoprodol has been shown to produce cross-tolerance to barbiturates & benzos

    Neat Facts I found online about Soma:

    According to 2009 National Survey on Drug Use and Health (NSDUH) data, 2.95 million people, aged 12 and older, used Soma for non-medical reasons in their lifetime.

    #112 Carisoprodol (Soma®) – Top 200 Prescribed Drugs


    Later,

    -WISH
    Last edited by Wish; 11-10-2011 at 07:19 PM.
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    The most I took was 8. I had to crawl on the floor because I couldn't walk. Mind you at 7, I was fine wasn't feeling much taking 1 every hour and a half. Now when I take them I just take 2 or 3 befor bed and lights out. This is from 2 years of off and on use.
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    Thanks for all the input. I have been taking both Soma and Xanax for many years and figured they were affecting each others effectiveness. Neither seem to work as good as they used to which has caused me to increase dosage, which does concern me. I have taken a big enough single dose (soma) to cause my speech to be ridiculous. Its wierd because my mind is still sharp, but my mouth just cant clearly talk. I can remember thinking to myself, "why the hell cant i talk normal". I function and walk fine, just cant have words pronounced clearly.

    Even with my tolerance 8 tabs would completely floor me. Most taken was 4 or 5 and it hits me hard. My metabolism might have something to do with it too. Most meds and dosages dont affect me nearly like other people that i know. I have zero opiate tolerance but i tried some DHC and it didnt really do all that much for me, if anything. Even Vicodin doesnt do much for me. I am also slightly larger than most... 6'4"ish, 275 lbs, pretty solid. Funny thing is i dont drink at all so just a small amount of alcohol will affect me.

    Anyway, i cant see myself taking 6 months off just to have a week or two of normal dosing before the tolerance builds again. Not worth it.

    I also dont see much purpose to recreational use. Any type of "buzz" you get from Soma lasts for a very short time and taking more wont get you a longer "buzz". I have found the morning dose makes me feel a little loose but the 2nd/3rd dose doesnt, just provides the intended relief. Kinda like if you have a headache and take some excedrin or something. Your headache goes away but its hard to pinpoint any exact "feeling" of it going away. If that makes sense.

    Quote Originally Posted by Wish View Post
    Let me begin this post by stating that I currently use Soma and this is neither an "anti, or pro Soma" post.
    What is your current dosage?
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    @Biggin2, I took 4 - 6 soma a day for over a year. Didn't have any tolerance or wd issues when I went off of it. Had surgery, didn't even think about it really.

    But I have heard again and again that tolerance is pretty much something one is stuck with, regardless of how long one goes off the med. I would suggest that it's time to find another muscle relaxer that works for you. Maybe throw in a small amount of valium if that soma calming effect is something that helps you.
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    Quote Originally Posted by Fireplaces View Post
    @Biggin2, I took 4 - 6 soma a day for over a year. Didn't have any tolerance or wd issues when I went off of it. Had surgery, didn't even think about it really.

    But I have heard again and again that tolerance is pretty much something one is stuck with, regardless of how long one goes off the med. I would suggest that it's time to find another muscle relaxer that works for you. Maybe throw in a small amount of valium if that soma calming effect is something that helps you.
    I can stop Soma without any wd issues. I have tried flexeril and it sucked, just made me wanna sleep. Not too many other muscle relaxers that work as well as Soma unfortunately. Currently i am prescribed Xanax and i get Soma online. I have been considering scraping both and just using Valium for both anxiety and muscle relaxation/spasms. Unfortunately i would have to go IOP for that as my doc didnt want to switch my Xanax to Valium. Havent been able to gain 100% confidence in a quality Valium source online though. MM seems the better choice but they seem wishy washy with their service and delivery.
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    Forgive my ignorance but since when have states started banning Soma? Or by states do you mean somewhere outside of the US? This is all news to me...
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    @depthoffield -- Certain states have scheduled Soma, so US vendors won't ship to those states.

    List of states here: http://en.wikipedia.org/wiki/Carisoprodol
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    @Biggin2 I take 2 to 3 350mg carisiprodal a few times a week. I only take it before bed. Also, I prefer Valium over Xanax anyday, but that's just me. If your seriouslty having that much trouble finding diazepam PM me and I'll try and point u in the right direction.

    @depthoffield Seems like there are more states that have banned Soma across state lines then states that permit it. Don't quote me on this but I believe the "no soma" states are:

    This product can't be shipped to the following states: (as per a reputible domestic OP)
    AL, AR, AZ, CT, DC, DE, FL, GA, HI, IA, ID, IN, KY, LA, MA, MN, MO, MT, NC, NM, NV, OH, OK, OR, PR, TX, UT, VA, VT, WA, WV

    Later,

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    Quote Originally Posted by depthoffield View Post
    Forgive my ignorance but since when have states started banning Soma? Or by states do you mean somewhere outside of the US? This is all news to me...
    Most of the states in the U.S. have scheduled Carisoprodol, not necessarily "banned", but that eliminates the ease of getting it and carries criminal charges if caught. Also Dr.'s dont like prescribing it.
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