any one taking pravastatin and eating frsh grapefruit?

[jackadine]

It has come to my attention that freh grapefruit does not affect how pravastatin works in ones body. Anyone taking this drug and eating grapefruit. I would love to be able to eat it again. I no longer have a warning on the label of my cholestrol medicine.

[tinmuning]

A study of grapefruit juice and lovastatin (a drug closely related to pravastatin) reported significantly increased lovastatin levels in people who drank grapefruit juice compared with water.This interaction has not yet been reported with pravastatin. Until more is known, it is prudent to avoid grapefruit juice during pravastatin therapy or discuss grapefruit juice intake (before consuming any) with the prescribing doctor. Although grapefruit could, in theory, be used to reduce the effective dose of the drug, current knowledge is not sufficient to guarantee against potentially harmful fluctuations in the levels of the drug in the body. Anyone taking pravastatin and drinking grapefruit juice would require very careful monitoring. The same effects might be seen from eating grapefruit as from drinking its juice.

[jackadine]

Thank you for your informative reply.