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The four most common adverse events of tizanidine are dry mouth, somnolence (drowsiness), asthenia (weakness, fatigue and/or tiredness) and dizziness. In addition, hypotension and bradycardia were observed. While the above side effects are dose-related and eventually disappear with discontinuation of the drug, some studies show that chronic use of the drug can cause liver injury (although rarely) & hypotension.
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