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Old 05-17-2009
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Is it dangerous taking Lamisil (Terbinafine) for months? Risk of liver damage
Hi,

I have a severe dermatophyte infection on my ankle - after only a week of taking Lamisil there is a marked improvement, however my Dermatologist seemed to think I will need to take it for at least three months.

According to a few things I've read, this long-term use is unadviseable, and can cause liver problems ranging from slight function impairment to complete liver failure - or perhaps nothing at all? Does anyone know for certain? I've experienced no side effects as yet, prior to this my liver function has been normal, and I haven't overtaxed it with any drugs or excessive alcohol consumption over the years.

Any personal/clinical experience? Any studies read? Opinions? I suppose ongoing liver function tests might be in order - I just wonder if anyone knows something definite (also, if there is a problem, does anyone know an alternative to terbinafine that poses less risk?)

Thanks in advance
Ah thanks. I'm taking the tablet, it's a pretty deep case, topical did nothing other than spread it more! The team of dermatologists I saw were a bit careless actually...
My GP is great but I don't know what his experience with the tablets are, if knows what risk (if any) long-term use poses...
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Old 05-18-2009
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Usually patients need to take Lamisil for skin infections for up to 4 to 6 months. However, you are right, long-term use of Lamisil is not advisable, that's why in cases where Lamisil needed to be taken for months, patients are monitored by their doctor on a monthly basis.
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