|Product quality / site reliability (weighting = 40%)||0.5|
|Ease of website use and range (weighting = 5%)||5.0|
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|Customer service (weighting = 10%. Optional)||3.0|
|Speed of delivery (weighting = 15%)||4.0|
Generic Tadafil 5mg - ? additives??
Have just received my order but am hesitant to try. Tablets are manufactured in India - this is not indicated on the Generic4all website and gives me some concern! Furthermore, an ingredient is Tartrazine as a colourant, which is a coal-tar based product linked to health concerns which is banned in a number of countries. Should I be concerned about the ingredients? Has anyone else tried these tablets?
September 25, 2012
2nd package was the same damned thing. I am calling tomorrow to rectify or get my card credited.
Here's what I found online about these:
Potential pharmacokinetic interactions between dapoxetine, a serotonin transporter inhibitor developed for the treatment of premature ejaculation (PE), and the phosphodiesterase-5 inhibitors tadalafil and sildenafil, agents used in the treatment of erectile dysfunction (ED), were investigated in an open-label, randomized, crossover study (n=24 men) comparing dapoxetine 60 mg, dapoxetine 60 mg+tadalafil 20 mg, and dapoxetine 60 mg+sildenafil 100 mg. Plasma concentrations of dapoxetine, tadalafil, and sildenafil were determined by liquid chromatography-tandem mass spectrometry. Tadalafil did not affect the pharmacokinetics of dapoxetine, whereas sildenafil increased the dapoxetine AUCinf by 22%; these effects were deemed not clinically important. Dapoxetine did not appear to affect the pharmacokinetics of tadalafil or sildenafil. Most adverse events were mild in nature. Thus, dapoxetine has no clinically important pharmacokinetic interactions with tadalafil or sildenafil, and the combinations are well tolerated.
Written by jim
October 06, 2012